Longevity Knowledge Hub

A study published in Nature examined the gut microbiomes of 160 Japanese centenarians, individuals aged 100 years or older. Researchers discovered that these centenarians possessed a distinct composition of gut bacteria compared to younger age groups. Notably, their microbiomes were enriched with microorganisms capable of producing unique secondary bile acids. These findings suggest a potential […]

Summary of the Key Findings The researchers conducted a comprehensive multiomics analysis—encompassing genomic, transcriptomic, metabolomic, proteomic, microbiomic, and epigenomic studies—on a supercentenarian (referred to as M116) who lived to the remarkable age of 117 years. Despite exceeding average life expectancy by over three decades, M116 remained in notably good health with no diagnosis of cancer, […]

In this in-depth conversation, Dr. Vonda Wright—a renowned orthopedic surgeon and longevity expert—discusses the intersection of musculoskeletal health, aging, and cognitive performance. She emphasizes a proactive and personalized approach to aging, health, and fitness through what she terms “precision longevity.” Her insights are rooted in decades of treating elite athletes and everyday people, focusing on […]

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